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SunDevil
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Posts: 82
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Three studies find that hydroxychloroquine reduces chances of contracting Covid
New Delhi: The Indian Council of Medical Research (ICMR), the country’s apex body in the field, has found that consuming the drug hydroxychloroquine
reduces the chances of getting infected with Covid-19.
As a result, ICMR released an advisory Friday to expand the usage of HCQ — an anti-malarial drug — as a preventive treatment against the novel
coronavirus.
The conclusion has been drawn on the basis of three studies conducted by the ICMR.
The advisory suggests surveillance workers, paramilitary and police personnel, as well as medical staff working in non-Covid hospitals and blocks to
start consuming the pill as “preventive therapy”.
https://theprint.in/health/hcq-breakthrough-icmr-finds-its-e...
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AKgringo
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Location: Anchorage, AK (no mas!)
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UPDATE......Retraction!
Here is today's update of the article that started this post; https://www.sciencedaily.com/releases/2020/05/200522113712.h...
Here is a Wall Street Journal link; https://www.msn.com/en-us/news/us/authors-retract-studies-th...
[Edited on 6-5-2020 by AKgringo]
If you are not living on the edge, you are taking up too much space!
"Could do better if he tried!" Report card comments from most of my grade school teachers. Sadly, still true!
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BajaTed
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Reward vs risk
The team also found that serious cardiac arrhythmias, which cause the lower chamber of the heart to beat rapidly and irregularly, were more common in
the groups receiving either of the four treatment regimens.
Es Todo Bueno
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SunDevil
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You might wonder if there is a hidden reason why a cheap generic drug that only costs a few cents gets such bad press. Ideas anyone?
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motoged
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No conspiracy..... just the facts . 
Don't believe everything you think....
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SFandH
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June 1st - National Center for Biotechnology Information, a branch of the National Institutes of Health:
"Oral hydroxychloroquine was authorized for emergency use by the US Food and Drug Administration (FDA) on March 28, 2020, to treat adult and
adolescent patients who weigh 50 kg or more hospitalized with COVID‐19 for whom a clinical trial is not available, or participation is not feasible
(https://www.fda.gov/media/136534/download). It was not approved for SARS‐CoV‐2 prevention. There are no scientifically established doses for
SARS‐CoV‐2. Although pharmacometric modeling and simulation has been used by several groups to propose potential regimens, 3 , 4 , 5 these are
targeted for hospitalized patients with advanced disease and no models have specifically evaluated regimens in the context of prophylaxis."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267462/
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SFandH
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And, from The Lancet:
"The Indian Council of Medical Research, under the Ministry of Health and Family Welfare, has recommended chemoprophylaxis with hydroxychloroquine
(400 mg twice on day 1, then 400 mg once a week thereafter) for asymptomatic health-care workers treating patients with suspected or confirmed
COVID-19, and for asymptomatic household contacts of confirmed cases.2 The document states “its use in prophylaxis is derived from available
evidence of benefit as treatment and supported by preclinical data”. Although some in-vitro evidence supports the antiviral activity of
hydroxychloroquine and its precursor chloroquine, there is no peer-reviewed publication that evaluates either drug for exposure prophylaxis of
SARS-CoV-2 infection. Even for treatment of diagnosed cases, only one small study reported faster nasopharyngeal viral clearance, with no data for
clinical improvement.3 This evidence, or the lack thereof, hardly justifies state-endorsed, widespread use of hydroxychloroquine for prophylaxis."
https://www.thelancet.com/journals/laninf/article/PIIS1473-3...
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SunDevil
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LANCET STUDY RETRACTION
The authors of the Lancet paper, 'Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: , have retracted their
study.
They were unable to complete an independent audit of the data underpinning their analysis. As a result, they have concluded that they 'can no longer
vouch for the veracity of the primary data sources.'
https://www.sciencedaily.com/releases/2020/05/200522113712.h...
The retraction happened a couple days ago and has not been widely reported.
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SFandH
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SunDevil, there are two issues.
1. Does hydroxy prevent COVID-19
2. Does hydroxy provide an effective treatment for patients with COVID-19.
The Lancet retraction had to do with a study for the second issue. They retracted the study not because of their conclusion that it is not an
effective treatment was wrong but because they could not authenticate the veracity of the data they based their conclusion upon.
In fact, what it is beginning to look like is that hydroxy is useful as a treatment but its efficacy as a preventative is still undecided.
The FDA has approved it for treatment but not for prevention....yet.
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SunDevil
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We should all try and keep an open mind, especially about things we are not familiar with.
Insults and vulgar language in someone's posts is a sign that they are the kind of person that Jeff Foxworthy jokes about.
Anyone wanting to learn more about the controversy around the retracted Lancet study can do their own research. Search online for something like 'why
was lancet covid study retracted' and you might stumble across the Guardian article below. The Guardian is a UK publication with a left-of-center
perspective and they have no love for anything Trump.
https://www.theguardian.com/world/2020/jun/04/covid-19-lance...
Nobody reputable has claimed the drug in question is a vaccine.
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BajaNaranja
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Looks like hydroxychloroquine will be on sale, red hat wearing believers should stock up.
"The US now has 66 million surplus anti-malaria pills after the FDA revoked an emergency waiver allowing chloroquine and hydroxychloroquine"
https://www.businessinsider.com/hydroxychloroquine-us-surplu...
The US now has 66 million excess anti-malaria pills after the FDA U-turned on chloroquine and hydroxychloroquine.
The FDA said the drugs were likely ineffective in treating COVID-19, and could be dangerous. It previously allowed the drugs to be used in
hospitalized coronavirus patients.
The government has sent out 31 million hydroxychloroquine tablets to state agencies, The New York Times reported, and now has 63 million left over,
alongside 3 million chloroquine pills.
Officials are now trying to figure out what to do with the excess drugs, and are working to "determine to available options," the Department of Health
and Human Services said.
Dr. Rick Bright, the former head of the US Biomedical Advanced Research and Development Authority (BARDA), said they "should be destroyed."
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mtgoat666
Select Nomad
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Location: San Diego
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Mood: Hot n spicy
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Quote: Originally posted by BajaNaranja  | Looks like hydroxychloroquine will be on sale, red hat wearing believers should stock up.
"The US now has 66 million surplus anti-malaria pills after the FDA revoked an emergency waiver allowing chloroquine and hydroxychloroquine"
https://www.businessinsider.com/hydroxychloroquine-us-surplu...
The US now has 66 million excess anti-malaria pills after the FDA U-turned on chloroquine and hydroxychloroquine.
The FDA said the drugs were likely ineffective in treating COVID-19, and could be dangerous. It previously allowed the drugs to be used in
hospitalized coronavirus patients.
The government has sent out 31 million hydroxychloroquine tablets to state agencies, The New York Times reported, and now has 63 million left over,
alongside 3 million chloroquine pills.
Officials are now trying to figure out what to do with the excess drugs, and are working to "determine to available options," the Department of Health
and Human Services said.
Dr. Rick Bright, the former head of the US Biomedical Advanced Research and Development Authority (BARDA), said they "should be destroyed."
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those malaria pills will be useful, after global warming introduces all the tropical mosquitoes into usa
Woke!
“...ask not what your country can do for you – ask what you can do for your country.” “My fellow citizens of the world: ask not what America
will do for you, but what together we can do for the freedom of man.”
Prefered gender pronoun: the royal we
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SFandH
Elite Nomad
Posts: 6962
Registered: 8-5-2011
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| Quote: Originally posted by BajaNaranja | "The US now has 66 million surplus anti-malaria pills after the FDA revoked an emergency waiver allowing chloroquine and hydroxychloroquine"
Dr. Rick Bright, the former head of the US Biomedical Advanced Research and Development Authority (BARDA), said they "should be
destroyed." |
Hey!! Dr. Rick, consider this.
Malaria occurs in more than 100 countries and territories. About half of the world's population is at risk. Large areas of Africa and South Asia and
parts of Central and South America, the Caribbean, Southeast Asia, the Middle East, and Oceania are considered areas where malaria transmission
occurs.
https://www.cdc.gov/malaria/about/faqs.html
[Edited on 6-18-2020 by SFandH]
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