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Author: Subject: The Key to Defeating COVID-19 Already Exists
SunDevil
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[*] posted on 7-24-2020 at 06:16 AM
The Key to Defeating COVID-19 Already Exists


The Key to Defeating COVID-19 Already Exists

By Harvey A. Risch, MD, PhD , Professor of Epidemiology, Yale School of Public Health

As professor of epidemiology at Yale School of Public Health, I have authored over 300 peer-reviewed publications and currently hold senior positions on the editorial boards of several leading journals. I am usually accustomed to advocating for positions within the mainstream of medicine, so have been flummoxed to find that, in the midst of a crisis, I am fighting for a treatment that the data fully support but which, for reasons having nothing to do with a correct understanding of the science, has been pushed to the sidelines. As a result, tens of thousands of patients with COVID-19 are dying unnecessarily. Fortunately, the situation can be reversed easily and quickly.

I am referring, of course, to the medication hydroxychloroquine. When this inexpensive oral medication is given very early in the course of illness, before the virus has had time to multiply beyond control, it has shown to be highly effective, especially when given in combination with the antibiotics azithromycin or doxycycline and the nutritional supplement zinc.

https://www.newsweek.com/key-defeating-covid-19-already-exis...

-----

For those that don't already know, Newsweek is not a right-wing publication. Please read the article at the link above before composing a politically inspired rebuttal.
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caj13
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[*] posted on 7-24-2020 at 07:43 AM


so "very early in the course of Illness" would mean during the time an individual is asymptomatic, or upon suspicion of the patient having been infected? Meaning extensive continuous testing would be required to identify the candidates that would benefit from the treatment?

[Edited on 7-24-2020 by caj13]

[Edited on 7-24-2020 by caj13]
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[*] posted on 7-24-2020 at 08:59 AM


Good point, the treatment won't be much use if you need to start it before you even have symptoms.

Looking at the article, there is a reference to an earlier article, "Early Outpatient Treatment of Symptomatic, High-Risk Covid-19 Patients that Should be Ramped-Up Immediately as Key to the Pandemic Crisis" which you can see at https://pubmed.ncbi.nlm.nih.gov/32458969/.

The abstract for this article says that "An outpatient treatment that prevents hospitalization is desperately needed" and "Five studies, including two controlled clinical trials, have demonstrated significant major outpatient treatment efficacy. Hydroxychloroquine+azithromycin has been used as standard-of-care in more than 300,000 older adults with multicomorbidities"
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[*] posted on 7-24-2020 at 10:37 AM


Hydroxychloroquine is the standard malaria preventive in Mexico. It has been taken long term with few adverse effects. That said Prilosec Max OTC has been shown to be effective in reducing the severity and length of symptoms if started when symptoms are first noticed. It is thought it works because it’s an “H2” inhibitor. It can’t be taken long term however as it looses effectiveness after about a month.

Many “at risk” individuals could be placed on Hydroxychloroquine for the 6 or so months until a vaccine is available.
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[*] posted on 7-24-2020 at 01:37 PM


Always started taking it before reaching the jungles of Central America. Pretty much standard regiment for a lot of preventive care procedures.
No big deal...until it becomes political.
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[*] posted on 7-24-2020 at 02:22 PM


He suggests "early use of hydroxychloroquine in high-risk patients", not as a universal prevention. A controversial measure, with studies showing both negative and positive outcomes. And - yes, early prevention would require a blanket testing, something akin to what UAE are doing now. Though Arabs don't use HCQ, they isolate positive asymptomatic cases, works same well. Probably - better, since an isolated patient is not spreading the infection regardless of whether he is taking HCQ or not.
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[*] posted on 7-24-2020 at 02:39 PM


He states “ it has demonstrated significant benefit in large hospital studies in Michigan and New York City when started within the first 24 to 48 hours after admission.” Meaning it shows significant increase in the outcome of those not asymptomatic but sick enough to be admitted to the hospital if started early enough. Read the article people, the answers to most of your questions are there.
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BajaNomad
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[*] posted on 7-25-2020 at 10:31 AM


first, I wish Dr. Risch would have taken the trouble to actually cite the studies he uses in his opinion piece (see the tab at the top of the page) . I am always suspect when one asks me to accept their interpretation of a 'study" without providing me an easy way to examine the original source myself. not real comfortable with anyone functioning as my sole filter of information.

Second of all - identifying Hydroxchlorequine as the "Key" to "defeating" covid? really? so taking a medication that helps some recover is the Key?

so why is it brazil has such high rates of illness, they are taking hydroxchloroquine by the handful, and they have huge death rates, that doesn't seem to match up!

in my opinion - THE KEY to defeating Covid is a functional vaccine, you want to stop a disease, you stop it from spreading, not just help those already sick get better. (you herd immunity people need to be a bit careful here, there is emerging evidence that those who are not strongly affected, but are infected, well it looks like their original immune response is not long lasting or very powerful, so they appear to be vulnerable to a second infection. )

But to each his own. would i take hydroxychloroquine if i was positive - probably, I have already volunteered for a trial here in the USA if i tested positive.

On the other hand - this whole discussion has the faint wiff of true believers trying to help their orange overlord regain his credibility as doctor in chief.
and to you true believers, I suggest you immediately get onto the drinking Bleach margaritas, huffing lysol, and getting sunshine blown up your sphincter! That , we know for sure, is the cure all for covid -

got it straight from the horses mouth - at least I think that was his mouth, it was a bit unclear which direction the horse was actually facing!
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[*] posted on 7-25-2020 at 10:57 AM


Quote: Originally posted by RFClark  
That said Prilosec Max OTC has been shown to be effective in reducing the severity and length of symptoms if started when symptoms are first noticed. It is thought it works because it’s an “H2” inhibitor. It can’t be taken long term however as it looses effectiveness after about a month.

Many “at risk” individuals could be placed on Hydroxychloroquine for the 6 or so months until a vaccine is available.


53,000 patient test group suggested taking Prilosec OTC a PPI led to a much greater health risk.
Prevacid a PPB is the one that let to health benefits.

“We found a strong, independent effect of using PPIs on risk of COVID-19, including a dose-response relationship with nearly a four-fold increased risk for twice daily dosing. But we found no relationship with the less powerful H2RAs, such as famotidine or cimetidine,” he added.


https://www.newswise.com/coronavirus/increased-risk-of-covid...
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[*] posted on 7-25-2020 at 11:29 AM


Let the red-hats, nation-wide be the test ‘dummies’ since they’re halfway there already.
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[*] posted on 7-25-2020 at 11:32 AM


Quote: Originally posted by SunDevil  
The Key to Defeating COVID-19 Already Exists

By Harvey A. Risch, MD, PhD , Professor of Epidemiology, Yale School of Public Health

As professor of epidemiology at Yale School of Public Health, I have authored over 300 peer-reviewed publications and currently hold senior positions on the editorial boards of several leading journals. I am usually accustomed to advocating for positions within the mainstream of medicine, so have been flummoxed to find that, in the midst of a crisis, I am fighting for a treatment that the data fully support but which, for reasons having nothing to do with a correct understanding of the science, has been pushed to the sidelines. As a result, tens of thousands of patients with COVID-19 are dying unnecessarily. Fortunately, the situation can be reversed easily and quickly.

I am referring, of course, to the medication hydroxychloroquine. When this inexpensive oral medication is given very early in the course of illness, before the virus has had time to multiply beyond control, it has shown to be highly effective, especially when given in combination with the antibiotics azithromycin or doxycycline and the nutritional supplement zinc.

https://www.newsweek.com/key-defeating-covid-19-already-exis...

-----

For those that don't already know, Newsweek is not a right-wing publication. Please read the article at the link above before composing a politically inspired rebuttal.


Or maybe the”key” is social distancing and mandatory masking!:light:

Its a funny world when common sense mask solution to airborne disease transmission is labeled a socialist anti-freedom commie conspiracy of george soros and bill gates.
Truly, the right wing nuts (and pusa) are cookoo

[Edited on 7-25-2020 by mtgoat666]




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[*] posted on 7-25-2020 at 01:00 PM


Isn't hydroxychloroquine the drug Trump was pushing when all this first started and everyone claimed it didn't work.
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[*] posted on 7-25-2020 at 01:16 PM


Quote: Originally posted by TMW  
Isn't hydroxychloroquine the drug Trump was pushing when all this first started and everyone claimed it didn't work.


Trump was taking it to prevent getting infected.

I think this thread is about taking it as a treatment after infection.


[Edited on 7-25-2020 by SFandH]




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Barry A.
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[*] posted on 7-25-2020 at 02:22 PM


Quote: Originally posted by SFandH  
Quote: Originally posted by TMW  
Isn't hydroxychloroquine the drug Trump was pushing when all this first started and everyone claimed it didn't work.


Trump was taking it to prevent getting infected.

I think this thread is about taking it as a treatment after infection.


[Edited on 7-25-2020 by SFandH]


That seems misleading, to me. Wasn't Pres. Trump taking it in case he became infected?? (not to "prevent getting infected") Words and phrases are tricky.

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[*] posted on 7-25-2020 at 03:29 PM


Quote: Originally posted by Barry A.  
Quote: Originally posted by SFandH  
Quote: Originally posted by TMW  
Isn't hydroxychloroquine the drug Trump was pushing when all this first started and everyone claimed it didn't work.


Trump was taking it to prevent getting infected.

I think this thread is about taking it as a treatment after infection.


[Edited on 7-25-2020 by SFandH]


That seems misleading, to me. Wasn't Pres. Trump taking it in case he became infected?? (not to "prevent getting infected") Words and phrases are tricky.



Could be, sorta like a pre-treatment. Maybe. Did he ever clearly say why he was taking it?

Hydroxychloroquine prevents malaria, so it is a prophylactic for that infection.




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[*] posted on 7-25-2020 at 04:51 PM


Quote: Originally posted by mtgoat666  

Or maybe the”key” is social distancing and mandatory masking!]

Both measures have been proven to work and don't have side-effects on your health. Also, isolation of positive asymptomatic cases. Distancing is a form of isolation. The problem is that half of the USA population perceive such measures as a threat to their freedom. Taking drugs is apparently more in line with North-American culture.

A vaccine will not protect you 100% or even 70% - it doesn't, with influenza. And it will be years before we'll know all the possible undesirable effects on human genes and immune system.

[Edited on 7-25-2020 by Alm]
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[*] posted on 7-25-2020 at 04:58 PM


Here is where it started on Nomad.

http://forums.bajanomad.com/viewthread.php?tid=94509
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[*] posted on 7-25-2020 at 05:01 PM


The big experiment coming up is the opening of schools.




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Alm
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[*] posted on 7-25-2020 at 05:10 PM


Quote: Originally posted by TMW  
Here is where it started on Nomad.

http://forums.bajanomad.com/viewthread.php?tid=94509

Started, ended, and started again.

But you are wrong - there was an earlier post by Bob & Susan where he/she suggested HCQ, don't remember based on what sources or whether there were any sources. Some nursing homes started it at that time, and then stopped.

In June FDA revoked the recommendation of emergency use of HCQ. The preventive effect of the drug is unclear.
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[*] posted on 7-25-2020 at 05:14 PM


200 mg de hidroxicloroquina 2 veces al día
500 mg de azitromicina 1 vez al día
220 mg de sulfato de zinc 1 vez al día




our website is:
http://www.mulege.org
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