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SunDevil
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The Key to Defeating COVID-19 Already Exists
The Key to Defeating COVID-19 Already Exists
By Harvey A. Risch, MD, PhD , Professor of Epidemiology, Yale School of Public Health
As professor of epidemiology at Yale School of Public Health, I have authored over 300 peer-reviewed publications and currently hold senior positions
on the editorial boards of several leading journals. I am usually accustomed to advocating for positions within the mainstream of medicine, so have
been flummoxed to find that, in the midst of a crisis, I am fighting for a treatment that the data fully support but which, for reasons having nothing
to do with a correct understanding of the science, has been pushed to the sidelines. As a result, tens of thousands of patients with COVID-19 are
dying unnecessarily. Fortunately, the situation can be reversed easily and quickly.
I am referring, of course, to the medication hydroxychloroquine. When this inexpensive oral medication is given very early in the course of illness,
before the virus has had time to multiply beyond control, it has shown to be highly effective, especially when given in combination with the
antibiotics azithromycin or doxycycline and the nutritional supplement zinc.
https://www.newsweek.com/key-defeating-covid-19-already-exis...
-----
For those that don't already know, Newsweek is not a right-wing publication. Please read the article at the link above before composing a politically
inspired rebuttal.
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caj13
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so "very early in the course of Illness" would mean during the time an individual is asymptomatic, or upon suspicion of the patient having been
infected? Meaning extensive continuous testing would be required to identify the candidates that would benefit from the treatment?
[Edited on 7-24-2020 by caj13]
[Edited on 7-24-2020 by caj13]
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SunDevil
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Good point, the treatment won't be much use if you need to start it before you even have symptoms.
Looking at the article, there is a reference to an earlier article, "Early Outpatient Treatment of Symptomatic, High-Risk Covid-19 Patients that
Should be Ramped-Up Immediately as Key to the Pandemic Crisis" which you can see at https://pubmed.ncbi.nlm.nih.gov/32458969/.
The abstract for this article says that "An outpatient treatment that prevents hospitalization is desperately needed" and "Five studies, including two
controlled clinical trials, have demonstrated significant major outpatient treatment efficacy. Hydroxychloroquine+azithromycin has been used as
standard-of-care in more than 300,000 older adults with multicomorbidities"
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RFClark
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Hydroxychloroquine is the standard malaria preventive in Mexico. It has been taken long term with few adverse effects. That said Prilosec Max OTC has
been shown to be effective in reducing the severity and length of symptoms if started when symptoms are first noticed. It is thought it works because
it’s an “H2” inhibitor. It can’t be taken long term however as it looses effectiveness after about a month.
Many “at risk” individuals could be placed on Hydroxychloroquine for the 6 or so months until a vaccine is available.
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paranewbi
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Always started taking it before reaching the jungles of Central America. Pretty much standard regiment for a lot of preventive care procedures.
No big deal...until it becomes political.
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Alm
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He suggests "early use of hydroxychloroquine in high-risk patients", not as a universal prevention. A controversial measure, with studies showing
both negative and positive outcomes. And - yes, early prevention would require a blanket testing, something akin to what UAE are doing now. Though
Arabs don't use HCQ, they isolate positive asymptomatic cases, works same well. Probably - better, since an isolated patient is not spreading the
infection regardless of whether he is taking HCQ or not.
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WestyWanderer
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He states “ it has demonstrated significant benefit in large hospital studies in Michigan and New York City when started within the first 24 to 48
hours after admission.” Meaning it shows significant increase in the outcome of those not asymptomatic but sick enough to be admitted to the
hospital if started early enough. Read the article people, the answers to most of your questions are there.
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BajaNomad
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Thread Moved 7-24-2020 at 04:34 PM |
caj13
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first, I wish Dr. Risch would have taken the trouble to actually cite the studies he uses in his opinion piece (see the tab at the top of the page)
. I am always suspect when one asks me to accept their interpretation of a 'study" without providing me an easy way to examine the original source
myself. not real comfortable with anyone functioning as my sole filter of information.
Second of all - identifying Hydroxchlorequine as the "Key" to "defeating" covid? really? so taking a medication that helps some recover is the
Key?
so why is it brazil has such high rates of illness, they are taking hydroxchloroquine by the handful, and they have huge death rates, that doesn't
seem to match up!
in my opinion - THE KEY to defeating Covid is a functional vaccine, you want to stop a disease, you stop it from spreading, not just help those
already sick get better. (you herd immunity people need to be a bit careful here, there is emerging evidence that those who are not strongly
affected, but are infected, well it looks like their original immune response is not long lasting or very powerful, so they appear to be vulnerable
to a second infection. )
But to each his own. would i take hydroxychloroquine if i was positive - probably, I have already volunteered for a trial here in the USA if i
tested positive.
On the other hand - this whole discussion has the faint wiff of true believers trying to help their orange overlord regain his credibility as doctor
in chief.
and to you true believers, I suggest you immediately get onto the drinking Bleach margaritas, huffing lysol, and getting sunshine blown up your
sphincter! That , we know for sure, is the cure all for covid -
got it straight from the horses mouth - at least I think that was his mouth, it was a bit unclear which direction the horse was actually facing!
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Stickers
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Quote: Originally posted by RFClark | That said Prilosec Max OTC has been shown to be effective in reducing the severity and length of symptoms if started when symptoms are first noticed.
It is thought it works because it’s an “H2” inhibitor. It can’t be taken long term however as it looses effectiveness after about a month.
Many “at risk” individuals could be placed on Hydroxychloroquine for the 6 or so months until a vaccine is available. |
53,000 patient test group suggested taking Prilosec OTC a PPI led to a much greater health risk.
Prevacid a PPB is the one that let to health benefits.
“We found a strong, independent effect of using PPIs on risk of COVID-19, including a dose-response relationship with nearly a four-fold increased
risk for twice daily dosing. But we found no relationship with the less powerful H2RAs, such as famotidine or cimetidine,” he added.
https://www.newswise.com/coronavirus/increased-risk-of-covid...
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Grenadiers
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Let the red-hats, nation-wide be the test ‘dummies’ since they’re halfway there already.
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mtgoat666
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Quote: Originally posted by SunDevil | The Key to Defeating COVID-19 Already Exists
By Harvey A. Risch, MD, PhD , Professor of Epidemiology, Yale School of Public Health
As professor of epidemiology at Yale School of Public Health, I have authored over 300 peer-reviewed publications and currently hold senior positions
on the editorial boards of several leading journals. I am usually accustomed to advocating for positions within the mainstream of medicine, so have
been flummoxed to find that, in the midst of a crisis, I am fighting for a treatment that the data fully support but which, for reasons having nothing
to do with a correct understanding of the science, has been pushed to the sidelines. As a result, tens of thousands of patients with COVID-19 are
dying unnecessarily. Fortunately, the situation can be reversed easily and quickly.
I am referring, of course, to the medication hydroxychloroquine. When this inexpensive oral medication is given very early in the course of illness,
before the virus has had time to multiply beyond control, it has shown to be highly effective, especially when given in combination with the
antibiotics azithromycin or doxycycline and the nutritional supplement zinc.
https://www.newsweek.com/key-defeating-covid-19-already-exis...
-----
For those that don't already know, Newsweek is not a right-wing publication. Please read the article at the link above before composing a politically
inspired rebuttal. |
Or maybe the”key” is social distancing and mandatory masking!
Its a funny world when common sense mask solution to airborne disease transmission is labeled a socialist anti-freedom commie conspiracy of george
soros and bill gates.
Truly, the right wing nuts (and pusa) are cookoo
[Edited on 7-25-2020 by mtgoat666]
Woke!
“...ask not what your country can do for you – ask what you can do for your country.” “My fellow citizens of the world: ask not what America
will do for you, but what together we can do for the freedom of man.”
Prefered gender pronoun: the royal we
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TMW
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Isn't hydroxychloroquine the drug Trump was pushing when all this first started and everyone claimed it didn't work.
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SFandH
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Quote: Originally posted by TMW | Isn't hydroxychloroquine the drug Trump was pushing when all this first started and everyone claimed it didn't work. |
Trump was taking it to prevent getting infected.
I think this thread is about taking it as a treatment after infection.
[Edited on 7-25-2020 by SFandH]
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Barry A.
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Quote: Originally posted by SFandH | Quote: Originally posted by TMW | Isn't hydroxychloroquine the drug Trump was pushing when all this first started and everyone claimed it didn't work. |
Trump was taking it to prevent getting infected.
I think this thread is about taking it as a treatment after infection.
[Edited on 7-25-2020 by SFandH] |
That seems misleading, to me. Wasn't Pres. Trump taking it in case he became infected?? (not to "prevent getting infected") Words and phrases are
tricky.
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SFandH
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Quote: Originally posted by Barry A. | Quote: Originally posted by SFandH | Quote: Originally posted by TMW | Isn't hydroxychloroquine the drug Trump was pushing when all this first started and everyone claimed it didn't work. |
Trump was taking it to prevent getting infected.
I think this thread is about taking it as a treatment after infection.
[Edited on 7-25-2020 by SFandH] |
That seems misleading, to me. Wasn't Pres. Trump taking it in case he became infected?? (not to "prevent getting infected") Words and phrases are
tricky.
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Could be, sorta like a pre-treatment. Maybe. Did he ever clearly say why he was taking it?
Hydroxychloroquine prevents malaria, so it is a prophylactic for that infection.
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Alm
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Both measures have been proven to work and don't have side-effects on your health. Also, isolation of positive asymptomatic cases. Distancing is a
form of isolation. The problem is that half of the USA population perceive such measures as a threat to their freedom. Taking drugs is apparently
more in line with North-American culture.
A vaccine will not protect you 100% or even 70% - it doesn't, with influenza. And it will be years before we'll know all the possible undesirable
effects on human genes and immune system.
[Edited on 7-25-2020 by Alm]
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TMW
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Here is where it started on Nomad.
http://forums.bajanomad.com/viewthread.php?tid=94509
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SFandH
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The big experiment coming up is the opening of schools.
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Alm
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Started, ended, and started again.
But you are wrong - there was an earlier post by Bob & Susan where he/she suggested HCQ, don't remember based on what sources or whether there
were any sources. Some nursing homes started it at that time, and then stopped.
In June FDA revoked the recommendation of emergency use of HCQ. The preventive effect of the drug is unclear.
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Bob and Susan
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200 mg de hidroxicloroquina 2 veces al día
500 mg de azitromicina 1 vez al día
220 mg de sulfato de zinc 1 vez al día
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